G
G. Y. Gillespie
Researcher at University of Alabama at Birmingham
Publications - 1
Citations - 540
G. Y. Gillespie is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Vascular permeability & Vascular endothelial growth factor A. The author has an hindex of 1, co-authored 1 publications receiving 525 citations.
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Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology.
TL;DR: VEGF released by glioma cells in situ most likely accounts for pathognomonic histopathologic and clinical features of GBM tumors in patients, including striking tumor angiogenesis, increased cerebral edema and hypercoagulability manifesting as focal tumor necrosis, deep vein thrombosis, or pulmonary embolism.