Gábor Tax

TL;DR: The role of P. acnes in acne pathogenesis is a topic of intense scientific debate and results suggest that Westernization strongly increases the dominance of the Propionibacterium genus in human skin compared with natural populations living more traditional lifestyles.

TL;DR: The results show that various P. acnes strains affect the cell-growth properties of these cells differentially, inducing cytotoxicity in a strain-specific and dose-dependent manner, and it is proposed that bacterially secreted propionic acid may contribute to the cytotoxic effect.

TL;DR: The TNFα −857 minor T allele was found to act as a protective factor in the study population in acne, and a higher occurrence of the minor −308 A allele in female acne patients was also noted.

TL;DR: A positive association was found between the minor T allele of the IL1A +4845(G>T) single nucleotide polymorphism (SNP) and acne, whereas no association was finding with respect to any alleles of the variable number of tandem repeats (VNTR) polymorphism of theIL1RN gene.

TL;DR: Leptin, the adipocyte‐secreted hormone that regulates weight, is known to link lipid metabolism with inflammation in various cell types, but its role in human sebocytes has not yet been investigated.