G
Gabriel Navarrete-Vázquez
Researcher at Universidad Autónoma del Estado de Morelos
Publications - 126
Citations - 3309
Gabriel Navarrete-Vázquez is an academic researcher from Universidad Autónoma del Estado de Morelos. The author has contributed to research in topics: Benzimidazole & In vivo. The author has an hindex of 29, co-authored 121 publications receiving 2869 citations. Previous affiliations of Gabriel Navarrete-Vázquez include Universidad Autónoma del Estado de México & National Autonomous University of Mexico.
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Journal ArticleDOI
Synthesis and antiparasitic activity of 1H-benzimidazole derivatives.
Juan Valdez,Roberto Cedillo,Alicia Hernández-Campos,Lilián Yépez,Francisco Hernández-Luis,Gabriel Navarrete-Vázquez,Amparo Tapia,Rafael Cortés,Manuel Hernández,Rafael Castillo +9 more
TL;DR: Although only compounds 3, 9 and 15 (2-methoxycarbonylamino derivatives) inhibited tubulin polymerization, these were not the most potent antiparasitic compounds.
Journal ArticleDOI
Synthesis and antiparasitic activity of 2-(Trifluoromethyl)benzimidazole derivatives
Gabriel Navarrete-Vázquez,Roberto Cedillo,Alicia Hernández-Campos,Lilián Yépez,Francisco Hernández-Luis,Juan Valdez,Raúl G. E. Morales,Rafael Cortés,Manuel Hernández,Rafael Castillo +9 more
TL;DR: 2-(Trifluoromethyl)benzimidazole derivatives substituted at the 1, 5, and 6-positions have been synthesized and in vitro tested against the protozoa Giardia lamblia, Entamnoeha histolytica, and the helminth Trichinella spiralis and results indicate that all the compounds tested are more active as antiprotozoal agents than Albendazole and Metronidazoles.
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Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation
Rolffy Ortiz-Andrade,Juan Carlos Sánchez-Salgado,Gabriel Navarrete-Vázquez,Scott P. Webster,Margareth Binnie,Sara García-Jiménez,Ismael León-Rivera,P. Cigarroa-Vazquez,Rafael Villalobos-Molina,Samuel Estrada-Soto,Samuel Estrada-Soto +10 more
TL;DR: The in vivo antidiabetic effect of naringenin (NG) in normoglycaemic and diabetic rat models through blood glucose (GLU) measurements following acute and subchronic time periods was determined.
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A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: Quercetin as a potential antidiabetic agent acting via 11β-Hydroxysteroid dehydrogenase type 1 inhibition
Mariana Torres-Piedra,Rolffy Ortiz-Andrade,Rafael Villalobos-Molina,Narender Singh,José L. Medina-Franco,Scott P. Webster,Margaret Binnie,Gabriel Navarrete-Vázquez,Samuel Estrada-Soto +8 more
TL;DR: Six structurally related flavonoids were investigated and quercetin, the most active compound, was docked into the crystal structure of 11beta-HSD1, indicating potential hydrogen bond interactions with hydroxyl groups of catalytic amino acid residues.
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Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP–1B: In vitro, in silico, and in vivo approaches
Juan José Ramírez-Espinosa,María Yolanda Rios,Sugey López-Martínez,Fabian López-Vallejo,José L. Medina-Franco,Paolo De Paoli,Guido Camici,Gabriel Navarrete-Vázquez,Rolffy Ortiz-Andrade,Samuel Estrada-Soto +9 more
TL;DR: Docking results suggested the potential binding of the triterpenic acids in a binding pocket next to the catalytic site of PTP-1B, and an extensive hydrogen bond network with the carboxyl group and Van der Waals interactions stabilize the protein-ligand complexes.