Gabriela Galiová

TL;DR: The principles behind epigenetic compartmentalization and the functional consequences of chromatin arrangement within interphase nuclei are summarized.

TL;DR: Observations indicate that lamin A/C deficiency causes not only reorganization of chromatin and some chromatin-associated domains, but also has an impact on the extent of chromosome condensation.

TL;DR: Comparisons in epigenetic and structural regulation of chromatin in nucleoli and the surrounding non-nucleolar region are focused on and the role of proteins, such as heterochromatin protein 1, fibrillarin, nucleolin, and upstream binding factor, are discussed in rRNA synthesis and processing.

TL;DR: ChIP‐on‐chip analysis revealed that differentiation results in a genome‐wide decrease in promoter H3K9 acetylation, and analyses point to chromosomes 11, 12, 17, and 19 as being critical for hESC pluripotency and endoderm‐like differentiation.

TL;DR: Pluripotent and differentiated hESCs have distinct nuclear patterns of heterochromatic structures and epigenetic marks, while relatively conserved gene density‐related radial chromatin distributions are already largely established in undifferentiated hES cells.