Gabriela Nosalova

TL;DR: The results showed that the cough suppressive activity of E. officinalis is dose-dependent, and a higher dose of this substance perorally was more effective, especially in decreasing the number of cough efforts, frequency of cough, and the intensity of cough attacks in inspirium and expirium was more pronounced.

TL;DR: In tests for antitussive activity in cats the fructan was found to be equally active as some non-narcotic, synthetic preparations used in clinical practice to treat coughing, and in mitogenic and comitogenic tests its biological response was comparable to that of the commercial Zymosan immunomodulator.

TL;DR: The rhamnogalacturonan, isolated from the roots of medicinal plant Althaea officinalis L., showed various biological effects on the citric acid-induced cough reflex and reactivity of airways smooth muscle in vitro and in vivo conditions and it seems that the cough suppression effect of the polymer is associated with the serotonergic 5-HT(2) receptor's function.

TL;DR: In this article, a water-soluble (4-O-methyl-α-d -glucurono)-d -xylan was isolated by alkaline extraction and fractionation of the crude hemicellulose, employing ion-exchange chromatography and gel filtration.

TL;DR: These extracts showed the ability to reduce citric acid-induced cough in awake guinea pigs after oral administration in a dose of 50mg/kg, and the strongest antitussive effect was found after application of the extract from G. glabra.