Gabriella Emri

TL;DR: Findings show that atorvastatin treatment favorably affected the lipid profile, increasing the activity of HDL-associated PON and decreasing the cytotoxic effect of oxidative stress.

TL;DR: The role of more than seventy molecules in necroptotic signaling is classified based on consistent in vitro or in vivo evidence to understand the molecular background of necroPTosis and to find opportunities where regulating the intensity and the modality of cell death could be exploited in clinical interventions.

TL;DR: Phys physiologic doses of sunlight can induce chromosomal aberrations at a level comparable with that observed after exposure to approximately 1 Gy of ionizing radiation, therefore, sunlight can be considered a potential inducer of chromosomalAberrations in skin cells, which may contribute to skin carcinogenesis.

TL;DR: The results corroborate the previous findings suggesting an association between an immunologically active tumor microenvironment and response to ipilimumab treatment, and propose new potential biomarkers for predicting treatment efficacy and disease outcome.

TL;DR: The healthy human skin with its effective antimicrobial defense system forms an efficient barrier against invading pathogens, making the easily collected sweat an ideal candidate for biomarker discoveries.