G
Gaigai Li
Researcher at Huazhong University of Science and Technology
Publications - 19
Citations - 270
Gaigai Li is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 14 publications receiving 111 citations.
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Journal ArticleDOI
Efficacy and safety of anti-inflammatory agents for the treatment of major depressive disorder: a systematic review and meta-analysis of randomised controlled trials
Shuang Bai,Wenliang Guo,Yangyang Feng,Hong Deng,Gaigai Li,Hao Nie,Guangyu Guo,Hai-Han Yu,Yang Ma,Jiahui Wang,Shiling Chen,Jie Jing,Jingfei Yang,Yingxin Tang,Zhouping Tang +14 more
TL;DR: Results of this systematic review suggest that anti-inflammatory agents play an antidepressant role in patients with MDD and are reasonably safe.
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Efficacy and safety of calcitonin-gene-related peptide binding monoclonal antibodies for the preventive treatment of episodic migraine – an updated systematic review and meta-analysis
TL;DR: The current body of evidence reveals that CGRP mAb is an effective and safe preventive treatment for episodic migraine.
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P2X7 receptor activation aggravates NADPH oxidase 2-induced oxidative stress after intracerebral hemorrhage.
Hong Deng,Ye Zhang,Gaigai Li,Hai-Han Yu,Shuang Bai,Guangyu Guo,Wenliang Guo,Yang Ma,Jiahui Wang,Na Liu,Chao Pan,Zhouping Tang +11 more
TL;DR: In this paper, the effects of activated P2X7R-associated oxidative stress after intracerebral hemorrhage were investigated in mice, and the results indicated that activation aggravated NOX2-induced oxidative stress through the activation of the ERK1/2 and NF-κB pathways.
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Upregulated TSG-6 Expression in ADSCs Inhibits the BV2 Microglia-Mediated Inflammatory Response
TL;DR: Following a treatment with TNFα, ADSCs can regulate the inflammatory response in LPS-activated BV2 microglia by upregulating TSG-6 expression, which itself is under the negative control of miR-214-5p.
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Met-RANTES preserves the blood–brain barrier through inhibiting CCR1/SRC/Rac1 pathway after intracerebral hemorrhage in mice
Jun Yan,Weilin Xu,Cameron Lenahan,Lei Huang,Umut Ocak,Jing Wen,Gaigai Li,Weiman He,Chen-Sheng Le,John H. Zhang,Ligen Mo,Jiping Tang +11 more
TL;DR: The authors showed that CCR5 inhibition by Met-R improves neurological deficits after ICH by preserving BBB integrity through inhibiting CCR1/SRC/Rac1 signaling pathway in mice.