G
Gangwu Mei
Researcher at Affymetrix
Publications - 5
Citations - 690
Gangwu Mei is an academic researcher from Affymetrix. The author has contributed to research in topics: Imputation (genetics) & Genome-wide association study. The author has an hindex of 5, co-authored 5 publications receiving 604 citations.
Papers
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Journal ArticleDOI
Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array.
Thomas J. Hoffmann,Mark N. Kvale,Stephanie Hesselson,Yiping Zhan,Christine Aquino,Yang Cao,Simon Cawley,Elaine Chung,Sheryl Connell,Jasmin L Eshragh,Marcia Ewing,Jeremy Gollub,Mary Henderson,Earl Hubbell,Carlos Iribarren,Jay Kaufman,Richard Lao,Yontao Lu,Dana Ludwig,Gurpreet K. Mathauda,William B. McGuire,Gangwu Mei,Sunita Miles,Matthew M. Purdy,Charles P. Quesenberry,Dilrini K. Ranatunga,Sarah Rowell,Marianne Sadler,Michael H. Shapero,Ling Shen,Tanushree R. Shenoy,David Smethurst,Stephen K. Van Den Eeden,Larry Walter,Eunice Wan,Reid Wearley,Teresa Webster,Wen Cc,Li Weng,Rachel A. Whitmer,Alan Williams,Simon Wong,Chia Zau,Andrea Finn,Catherine Schaefer,Pui-Yan Kwok,Neil Risch,Neil Risch +47 more
TL;DR: The development of a next-generation microarray based on the new highly-efficient Affymetrix Axiom genotyping technology that is used to genotype individuals of European ancestry from the Kaiser Permanente Research Program on Genes, Environment and Health (RPGEH).
Journal ArticleDOI
Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
Mark N. Kvale,Stephanie Hesselson,Thomas J. Hoffmann,Yang Cao,David Chan,Sheryl Connell,Lisa A. Croen,Brad Dispensa,Jasmin L Eshragh,Andrea Finn,Jeremy Gollub,Carlos Iribarren,Eric Jorgenson,Lawrence H. Kushi,Richard Lao,Yontao Lu,Dana Ludwig,Gurpreet K. Mathauda,William B. McGuire,Gangwu Mei,Sunita Miles,Michael Mittman,Mohini Patil,Charles P. Quesenberry,Dilrini K. Ranatunga,Sarah Rowell,Marianne Sadler,Lori C. Sakoda,Michael H. Shapero,Ling Shen,Tanu Shenoy,David Smethurst,Carol P. Somkin,Stephen K. Van Den Eeden,Lawrence Walter,Eunice Wan,Teresa Webster,Rachel A. Whitmer,Simon Wong,Chia Zau,Yiping Zhan,Catherine Schaefer,Pui-Yan Kwok,Neil Risch,Neil Risch +44 more
TL;DR: The high quality and large scale of genotype data created on this cohort, in conjunction with comprehensive longitudinal data from the KP electronic health records of participants, will enable a broad range of highly powered genome-wide association studies on a diversity of traits and conditions.
Journal ArticleDOI
Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm
Thomas J. Hoffmann,Yiping Zhan,Mark N. Kvale,Stephanie Hesselson,Jeremy Gollub,Carlos Iribarren,Yontao Lu,Gangwu Mei,Matthew M. Purdy,Charles P. Quesenberry,Sarah Rowell,Michael H. Shapero,David Smethurst,Carol P. Somkin,Stephen K. Van Den Eeden,Larry Walter,Teresa Webster,Rachel A. Whitmer,Andrea Finn,Catherine Schaefer,Pui-Yan Kwok,Neil Risch,Neil Risch +22 more
TL;DR: Four custom Axiom genotyping arrays were designed for a genome-wide association study of 100,000 participants from the Kaiser Permanente Research Program on Genes, Environment and Health and are valuable additions for large-scale GWA studies.
Journal ArticleDOI
Gene structure-based splice variant deconvolution using a microarry platform
Hui Wang,Earl Hubbell,Jing-shan Hu,Gangwu Mei,Melissa S. Cline,Gang Lu,Tyson A. Clark,Michael A. Siani-Rose,Manuel Ares,David Kulp,David Haussler +10 more
TL;DR: This work developed a gene structure-based algorithm to determine the relative abundance of known splice variants, which produces the relative concentration of each variant, as well as an affinity term associated with each probe.
Patent
Analysis of methylation using nucleic acid arrays
Yanxiang Cao,Shivani Nautiyal,Charles Garrett Miyada,Christopher Davies,Gangwu Mei,Alan Williams,Eric B. Schell,John E. Blume +7 more
TL;DR: In this article, a preferred aspect array comprising a plurality of probes complementary to a plurality identified CpG islands in the human, mouse and rat genome is disclosed. And the arrays may be used to detect methylation in samples from human, mice and rat genomes.