J
Jeremy Gollub
Researcher at Affymetrix
Publications - 10
Citations - 942
Jeremy Gollub is an academic researcher from Affymetrix. The author has contributed to research in topics: Genome-wide association study & Genotype. The author has an hindex of 6, co-authored 10 publications receiving 824 citations.
Papers
More filters
Journal ArticleDOI
Impact of cellular miRNAs on circulating miRNA biomarker signatures.
TL;DR: It is found that measurement of circulating miRNA levels are frequently confounded by varying levels of cellular miRNAs of different hematopoietic origins, and the intrinsic variability of circulate miRNA species investigated in subsets of healthy males and females.
Journal ArticleDOI
Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array.
Thomas J. Hoffmann,Mark N. Kvale,Stephanie Hesselson,Yiping Zhan,Christine Aquino,Yang Cao,Simon Cawley,Elaine Chung,Sheryl Connell,Jasmin L Eshragh,Marcia Ewing,Jeremy Gollub,Mary Henderson,Earl Hubbell,Carlos Iribarren,Jay Kaufman,Richard Lao,Yontao Lu,Dana Ludwig,Gurpreet K. Mathauda,William B. McGuire,Gangwu Mei,Sunita Miles,Matthew M. Purdy,Charles P. Quesenberry,Dilrini K. Ranatunga,Sarah Rowell,Marianne Sadler,Michael H. Shapero,Ling Shen,Tanushree R. Shenoy,David Smethurst,Stephen K. Van Den Eeden,Larry Walter,Eunice Wan,Reid Wearley,Teresa Webster,Wen Cc,Li Weng,Rachel A. Whitmer,Alan Williams,Simon Wong,Chia Zau,Andrea Finn,Catherine Schaefer,Pui-Yan Kwok,Neil Risch,Neil Risch +47 more
TL;DR: The development of a next-generation microarray based on the new highly-efficient Affymetrix Axiom genotyping technology that is used to genotype individuals of European ancestry from the Kaiser Permanente Research Program on Genes, Environment and Health (RPGEH).
Journal ArticleDOI
Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
Mark N. Kvale,Stephanie Hesselson,Thomas J. Hoffmann,Yang Cao,David Chan,Sheryl Connell,Lisa A. Croen,Brad Dispensa,Jasmin L Eshragh,Andrea Finn,Jeremy Gollub,Carlos Iribarren,Eric Jorgenson,Lawrence H. Kushi,Richard Lao,Yontao Lu,Dana Ludwig,Gurpreet K. Mathauda,William B. McGuire,Gangwu Mei,Sunita Miles,Michael Mittman,Mohini Patil,Charles P. Quesenberry,Dilrini K. Ranatunga,Sarah Rowell,Marianne Sadler,Lori C. Sakoda,Michael H. Shapero,Ling Shen,Tanu Shenoy,David Smethurst,Carol P. Somkin,Stephen K. Van Den Eeden,Lawrence Walter,Eunice Wan,Teresa Webster,Rachel A. Whitmer,Simon Wong,Chia Zau,Yiping Zhan,Catherine Schaefer,Pui-Yan Kwok,Neil Risch,Neil Risch +44 more
TL;DR: The high quality and large scale of genotype data created on this cohort, in conjunction with comprehensive longitudinal data from the KP electronic health records of participants, will enable a broad range of highly powered genome-wide association studies on a diversity of traits and conditions.
Journal ArticleDOI
Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm
Thomas J. Hoffmann,Yiping Zhan,Mark N. Kvale,Stephanie Hesselson,Jeremy Gollub,Carlos Iribarren,Yontao Lu,Gangwu Mei,Matthew M. Purdy,Charles P. Quesenberry,Sarah Rowell,Michael H. Shapero,David Smethurst,Carol P. Somkin,Stephen K. Van Den Eeden,Larry Walter,Teresa Webster,Rachel A. Whitmer,Andrea Finn,Catherine Schaefer,Pui-Yan Kwok,Neil Risch,Neil Risch +22 more
TL;DR: Four custom Axiom genotyping arrays were designed for a genome-wide association study of 100,000 participants from the Kaiser Permanente Research Program on Genes, Environment and Health and are valuable additions for large-scale GWA studies.
Journal ArticleDOI
Genome-wide maps of circulating miRNA biomarkers for ulcerative colitis.
Radha Duttagupta,Sharon DiRienzo,Rong Jiang,Jessica Bowers,Jeremy Gollub,Jessica Kao,Keith R. Kearney,David S. Rudolph,Noor Dawany,Michael K. Showe,Tom Stamato,Robert Getts,Keith W. Jones +12 more
TL;DR: Analysis of whole genome maps of circulating miRNAs in micro-vesicles, Peripheral Blood Mononuclear Cells and platelets outlines a promising catalog of novel platelet-derived miRNA biomarkers of clinical utility and provides insight into the potential biological function of these candidates in disease pathogenesis.