Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications

Microemulsion-based media as novel drug delivery systems

"Nanoantibiotics": a new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era.

Nanosizing: a formulation approach for poorly-water-soluble compounds.

Chemistries that Facilitate Nanotechnology Kim E. Sapsford,† W. Russ Algar, Lorenzo Berti, Kelly Boeneman Gemmill,‡ Brendan J. Casey,† Eunkeu Oh, Michael H. Stewart, and Igor L. Medintz*,‡ †Division of Biology, Department of Chemistry and Materials Science, Office of Science and Engineering Laboratories, U.S. Food and Drug Administration, Silver Spring, Maryland 20993, United States ‡Center for Bio/Molecular Science and Engineering Code 6900 and Division of Optical Sciences Code 5611, U.S. Naval Research Laboratory, Washington, D.C. 20375, United States College of Science, George Mason University, 4400 University Drive, Fairfax, Virginia 22030, United States Department of Biochemistry and Molecular Medicine, University of California, Davis, School of Medicine, Sacramento, California 95817, United States Sotera Defense Solutions, Crofton, Maryland 21114, United States

Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology.

Gelatin-stabilised microemulsion-based organogels: rheology and application in iontophoretic transdermal drug delivery.

Fig. 1. Proposed MBG structure based on neutron scattc ’&. The MBG is an effective immobilisation matrix for proteins such as lipase. Dispersal occurs at the molecular level with full retention of catalytic activity, and enhanced stability. The MBG is thermodynamically stable, and is structurally stable in contact with apolar solvents, including the parent hydrocarbon. This feature facilitates the granulation of protein-containing MBGs and their exploitation in kilogram-scale biotransformations in organic media (Jenta et al, 1997; 1997).

Gareth D. Rees

Papers

Microemulsion-based media as novel drug delivery systems

Gelatin-stabilised microemulsion-based organogels: rheology and application in iontophoretic transdermal drug delivery.

Microemulsion-based organogels: A novel matrix for transdermal drug delivery