G
Gary D. Hunter
Researcher at University of Strathclyde
Publications - 3
Citations - 1638
Gary D. Hunter is an academic researcher from University of Strathclyde. The author has contributed to research in topics: Protease-activated receptor & Proinflammatory cytokine. The author has an hindex of 3, co-authored 3 publications receiving 1611 citations.
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Journal Article
Proteinase-Activated Receptors
TL;DR: The role of thrombin in such processes as wound healing and the evidence implicating PAR-1 in vascular disorders and cancer are described and advances in the understanding ofPAR-1-mediated intracellular signaling and receptor desensitization are identified.
Journal ArticleDOI
Essential role for proteinase-activated receptor-2 in arthritis
William R. Ferrell,John C. Lockhart,EB Kelso,Lynette Dunning,Robin Plevin,Stephen Meek,Andrew J.H. Smith,Gary D. Hunter,John S. McLean,Frances McGarry,Robert Ramage,Lu Jiang,Toru Kanke,Junichi Kawagoe +13 more
TL;DR: It is demonstrated that proteinase-activated receptor-2 (PAR-2) plays a pivotal role in mediating chronic inflammation, thereby identifying a novel and important therapeutic target for the management of chronic inflammatory diseases such as rheumatoid arthritis.
Journal ArticleDOI
Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear.
Junichi Kawagoe,Toshiaki Takizawa,Jiro Matsumoto,Masaki Tamiya,Stephen Meek,Andrew J.H. Smith,Gary D. Hunter,Robin Plevin,Naohiro Saito,Toru Kanke,Mikio Fujii,Yasushi Wada +11 more
TL;DR: The results strongly suggest that PAR-2 plays a crucial role in type IV allergic dermatitis but not in type I allergic Dermatitis.