G
Gayle E. Lester
Researcher at University of North Carolina at Chapel Hill
Publications - 42
Citations - 2718
Gayle E. Lester is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Bone mineral & Bone density. The author has an hindex of 25, co-authored 42 publications receiving 2575 citations. Previous affiliations of Gayle E. Lester include Baylor College of Medicine & Medical University of South Carolina.
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Journal ArticleDOI
Increased Rate of Fractures and Severe Kyphosis: Sequelae of Living into Adulthood with Cystic Fibrosis
Robert M. Aris,Jordan B. Renner,Andrew D. Winders,Hope E. Buell,Debra B. Riggs,Gayle E. Lester,David A. Ontjes +6 more
TL;DR: Results show that osteopenia may occur as early as the first decade of life in patients with cystic fibrosis and that bone loss accelerates during adolescence and early adulthood.
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Effect of cefazolin and vancomycin on osteoblasts in vitro
TL;DR: Vancomycin is less toxic than is cefazolin to osteoblasts at higher concentrations and may be a better antibiotic for local administration in the treatment of similarly sensitive bacterial infections.
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Efficacy of pamidronate for osteoporosis in patients with cystic fibrosis following lung transplantation.
Robert M. Aris,Gayle E. Lester,Jordan B. Renner,Andrew D. Winders,A. Denene Blackwood,Robert K. Lark,David A. Ontjes +6 more
TL;DR: It is concluded that pamidronate was more effective than control in improving bone mineral density after lung transplantation in patients with CF and appears to be one of the most promising agents studied to date for posttransplant osteoporosis.
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Association between low levels of 1,25-dihydroxyvitamin D and breast cancer risk.
Esther C. Janowsky,Gayle E. Lester,Clarice R. Weinberg,Robert C. Millikan,Joellen M. Schildkraut,Peter A. Garrett,Barbara S. Hulka +6 more
TL;DR: Data are consistent with a protective effect of 1,25-D for breast cancer in white women, and the association inwhite women was stronger in women above the median age of 54 than in younger women.
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An in vivo model of degenerative disc disease.
TL;DR: The model appears to be a reasonable tool for the preliminary in vivo evaluation of proposed treatments for degenerative disc disease and diminished proteoglycan content, loss of NP cells, and increased stiffness of the disc.