G
Geert Jan Biessels
Researcher at Utrecht University
Publications - 459
Citations - 28967
Geert Jan Biessels is an academic researcher from Utrecht University. The author has contributed to research in topics: Dementia & Diabetes mellitus. The author has an hindex of 79, co-authored 417 publications receiving 23364 citations. Previous affiliations of Geert Jan Biessels include VU University Medical Center & VU University Amsterdam.
Papers
More filters
Journal ArticleDOI
Risk of dementia in diabetes mellitus: a systematic review
TL;DR: The findings of mechanistic studies suggest that vascular disease and alterations in glucose, insulin, and amyloid metabolism underlie the pathophysiology of dementia, but which of these mechanisms are clinically relevant is unclear.
Journal ArticleDOI
Cognition and synaptic plasticity in diabetes mellitus
TL;DR: The multifactorial pathogenesis of diabetic encephalopathy is not yet completely understood, but clearly shares features with brain ageing and the pathogenic of diabetic neuropathy, but probably also defects in insulin action in the brain.
Journal ArticleDOI
The Effects of Type 1 Diabetes on Cognitive Performance: A meta-analysis
Augustina M. A. Brands,Geert Jan Biessels,Edward H.F. de Haan,L. Jaap Kappelle,Roy P. C. Kessels +4 more
TL;DR: Lowered cognitive performance in diabetic patients appeared to be associated with the presence of microvascular complications but not with the occurrence of severe hypoglycemic episodes or with poor metabolic control.
Journal ArticleDOI
Cognition and diabetes: a lifespan perspective.
TL;DR: This Personal View investigates the hypothesis that clinically relevant diabetes-related cognitive decrements mainly occur at two crucial periods in life: when the brain is developing in childhood, and when thebrain undergoes neurodegenerative changes associated with ageing.
Journal ArticleDOI
Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications.
Geert Jan Biessels,Florin Despa +1 more
TL;DR: The evolving insights from studies on risk factors, brain imaging and neuropathology are reviewed, which provide important clues on mechanisms of both the subtle cognitive decrements and the more severe stages of cognitive dysfunction.