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Geert Verbeke
Researcher at Katholieke Universiteit Leuven
Publications - 368
Citations - 19766
Geert Verbeke is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Random effects model & Generalized linear mixed model. The author has an hindex of 58, co-authored 355 publications receiving 18329 citations. Previous affiliations of Geert Verbeke include The Catholic University of America & University of Hasselt.
Papers
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Book
Linear Mixed Models for Longitudinal Data
Geert Verbeke,Geert Molenberghs +1 more
TL;DR: Using data of 955 men, Brant et al showed that the average rates of increase of systolic blood pressure (SBP) are smallest in the younger age groups, and greatest in the older agegroups, and that obese individuals tend to have a higher SBP than non-obese individuals.
Book
Models for Discrete Longitudinal Data
Geert Molenberghs,Geert Verbeke +1 more
TL;DR: This paper presents a meta-analysis of generalized Linear Mixed Models for Gaussian Longitudinal Data and its applications to Hierarchical Models and Random-effects Models.
Journal ArticleDOI
Chromosome instability is common in human cleavage-stage embryos
Evelyne Vanneste,Thierry Voet,Cédric Le Caignec,Cédric Le Caignec,Michèle Ampe,Peter Konings,Cindy Melotte,Sophie Debrock,Mustapha Amyere,Miikka Vikkula,Frans Schuit,Jean-Pierre Fryns,Geert Verbeke,Thomas D'Hooghe,Yves Moreau,Joris Vermeesch +15 more
TL;DR: In this article, a new array-based method allowed screening of genome-wide copy number and loss of heterozygosity in single cells, which revealed not only mosaicism for whole-chromosome aneuploidies and uniparental disomies in most cleavage-stage embryos but also frequent segmental deletions, duplications and amplifications that were reciprocal in sister blastomeres, implying the occurrence of breakage-fusion-bridge cycles.
Book ChapterDOI
Random Effects Models for Longitudinal Data
TL;DR: This chapter gives an overview of frequently used mixed models for continuous as well as discrete longitudinal data, with emphasis on model formulation and parameter interpretation.
Journal ArticleDOI
A Linear Mixed-Effects Model with Heterogeneity in the Random-Effects Population
Geert Verbeke,Emmanuel Lesaffre +1 more
TL;DR: In this paper, the authors investigated the impact of the normality assumption for random effects on their estimates in the linear mixed-effects model and showed that if the distribution of random effects is a finite mixture of normal distributions, then the random effects may be badly estimated if normality is assumed.