G
Gene S. Lee
Researcher at University of California, San Francisco
Publications - 2
Citations - 278
Gene S. Lee is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Steatosis & Fatty liver. The author has an hindex of 2, co-authored 2 publications receiving 251 citations.
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Journal ArticleDOI
Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1.
Gizem Rizki,Lorenzo Arnaboldi,Bianca Gabrielli,Jim Yan,Gene S. Lee,Ray K. Ng,Scott M. Turner,Thomas M. Badger,Robert E. Pitas,Jacquelyn J. Maher +9 more
TL;DR: It is found that MCD feeding causes profound hepatic suppression of the gene encoding stearoyl-coenzyme A desaturase-1 (SCD-1) in the liver, which likely contributes to hypermetabolism and weight loss.
Journal ArticleDOI
Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury.
TL;DR: Results indicate that dietary PUFAs promote hepatic inflammation but not hepatotoxicity in the MCD model of liver disease, and emphasize that individual dietary nutrients can make specific contributions to steatohepatitis.