Scott M. Turner

TL;DR: 2H2O labeling of dR in DNA allows safe, convenient, reproducible, and inexpensive measurement of cell proliferation in humans and experimental animals and is well suited for slow turnover cells.

TL;DR: It is concluded that altered CHO intake alters HGP specifically and in a dose-dependent manner, that HGP may mediate the effects of CHO on whole-body fuel selection both by providing substrate and by altering serum insulin concentrations, that altered lipolysis and tissue oxidation efficiency contribute to changes in fat oxidation, and that surplus CHO is not substantially converted by the liver to fat as it spares fat oxidation.

TL;DR: It is found that MCD feeding causes profound hepatic suppression of the gene encoding stearoyl-coenzyme A desaturase-1 (SCD-1) in the liver, which likely contributes to hypermetabolism and weight loss.

TL;DR: Hepatic gluconeogenic flux into glycogen and glycogen turnover persist during fasting in humans, reconciling inconsistencies in the literature and interposing another locus of control in the normal pathway of GP.

TL;DR: A critical role is demonstrated for Mfge8 in decreasing the severity of murine tissue fibrosis by facilitating the removal of accumulated collagen through binding and targeting collagen for cellular uptake through its discoidin domains.