10. Patented Literature 2616 10.1. Esterification 2616 10.2. Ether Formation 2619 10.2.1. Etherification without Cyclization 2619 10.2.2. Etherification with Cyclization 2624 10.3. N-Alkylation 2625 10.4. Other Reactions 2627 11. Summary and Outlook 2628 12. Note Added in Proof 2628 13. Abbreviations Used in This Review 2629 14. Acknowledgments 2629 15. Supporting Information Available 2630 16. References 2630

Mitsunobu and Related Reactions: Advances and Applications

2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products.

Compounds having structure (A) are useful to inhibit serine protease enzymes, such as TF/factor VIIa, factor Xa, thrombin and kallikrein. These compounds may be used in methods of preventing and/or treating clotting disorders.

Serine protease inhibitors

Recent developments in hydantoin chemistry. a review

Synthesis of Nonracemic Phosphonates

Synthesis of pseudonucleosides containing chiral sulfahydantoins as aglycone (II)

A new family of potential oncostatics: 2-chloroethylnitrososulfamides (CENS)--I. Synthesis, structure, and pharmacological evaluation (preliminary results).

Synthèse de “sulfahydatoïnes” chirales. Aspects stéréochimiques et protection régiospécifique.

An efficient and original stereocontrolled transannular rearrangement starting from activated 2,5-diketopiperazines has been developed, an opportunity for the medicinal chemistry field, which requests access to novel biological scaffolds. This powerful ring contraction, which can be related to a stereoselective aza-version of the Chan rearrangement, allows for example the one-step synthesis of various tetramic acids, access to 2-disubstituted statins, or the synthesis of relevant lactam-constrained dipeptide mimetics using a TRAL–RCM sequence.

Transannular rearrangement of activated 2,5-diketopiperazines: a key route to original scaffolds.

Synthesis of n-sulfamoyloxazolidinones and -perhydrooxazinones reactivity and use as donors in the transsulfamoylation reaction; application to the preparation of 2-chloroethylnitrososulfamides. IV

Georges Dewynter

Papers

Synthesis of pseudonucleosides containing chiral sulfahydantoins as aglycone (II)

A new family of potential oncostatics: 2-chloroethylnitrososulfamides (CENS)--I. Synthesis, structure, and pharmacological evaluation (preliminary results).

Synthèse de “sulfahydatoïnes” chirales. Aspects stéréochimiques et protection régiospécifique.

Transannular rearrangement of activated 2,5-diketopiperazines: a key route to original scaffolds.

Synthesis of n-sulfamoyloxazolidinones and -perhydrooxazinones reactivity and use as donors in the transsulfamoylation reaction; application to the preparation of 2-chloroethylnitrososulfamides. IV