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Showing papers by "Gerard J. J. M. Borsboom published in 2011"


Journal ArticleDOI
TL;DR: The long-term effects of lung cancer computed tomography screening on health-related quality of life (HRQoL) and anxiety (Spielberger State-Trait Anxiety Inventory) and lung cancer-specific distress (impact of event scale (IES) have not yet been investigated.
Abstract: The long-term effects of lung cancer computed tomography (CT) screening on health-related quality of life (HRQoL) have not yet been investigated In the Dutch–Belgian Randomised Lung Cancer Screening Trial (NELSON trial), 1,466 participants received questionnaires before randomisation (T0), 2 months after baseline screening (screen group only; T1) and at 2-yr follow-up (T2) HRQoL was measured as generic HRQoL (12-item short-form questionnaire and EuroQoL questionnaire), anxiety (Spielberger State-Trait Anxiety Inventory) and lung cancer-specific distress (impact of event scale (IES)) Repeated measures of ANOVA were used to analyse differences between the screen and control groups, and between indeterminate (requiring a follow-up CT) and negative screening result groups At T0 and T2 there were no significant differences in HRQoL scores over time between the screen and control groups, or between the indeterminate or negative second-round screening result group There was a temporary increase in IES scores after an indeterminate baseline result (T0: mean 40 (95% CI 28–53); T1: mean 78 (95% CI 65–90); T2: mean 45 (95% CI 33–58)) At 2-yr follow-up, the HRQoL of screened subjects was similar to that of control subjects, the unfavourable short-term effects of an indeterminate baseline screening result had resolved and an indeterminate result at the second screening round had no impact on HRQoL

110 citations


Journal ArticleDOI
TL;DR: There are large age-group and regional differences in CHB prevalence in Turkey, where CHB remains a serious health problem.
Abstract: Background To provide a clear picture of the current hepatitis B situation, the authors performed a systematic review to estimate the age- and region-specific prevalence of chronic hepatitis B (CHB) in Turkey.

97 citations


Journal ArticleDOI
TL;DR: Evidence is provided for the effectiveness of the multi-component intervention Lekker Fit! among pupils of grades 3-5 and adds to the growing body of evidence that school-based programs with a focus on PA are most effective in reducing childhood obesity.
Abstract: Objectives. The purpose of this study was to evaluate the effect of a school-based intervention program to reduce overweight and improve fitness in primary school children. Methods. A cluster rando...

83 citations