G
Gérard Keith
Researcher at Centre national de la recherche scientifique
Publications - 155
Citations - 6643
Gérard Keith is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Transfer RNA & RNA. The author has an hindex of 41, co-authored 155 publications receiving 6466 citations. Previous affiliations of Gérard Keith include Institut national de la recherche agronomique & University of Kent.
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A new yeast poly(A) polymerase complex involved in RNA quality control.
Štěpánka Vaňáčová,Jeannette Wolf,Georges Martin,Diana Blank,Sabine Dettwiler,Arno Friedlein,Hanno Langen,Gérard Keith,Walter Keller +8 more
TL;DR: Comparison of native tRNAi Met with its in vitro transcribed unmodified counterpart revealed that the unmodified RNA was preferentially polyadenylated by affinity-purified Trf4 complex from yeast, as well as by complexes reconstituted from recombinant components, suggesting that the Trf 4 complex can discriminate between native tRNAs and molecules that are incorrectly folded.
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Walking along the rabies genome: is the large G-L intergenic region a remnant gene?
TL;DR: Evidence for the existence of a remnant protein gene in the 423 nucleotide long G-L intergenic region of rabies intergenic regions is presented and is discussed in terms of the evolution of unsegmented negative-strand RNA viruses.
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HIV-1 reverse transcriptase specifically interacts with the anticodon domain of its cognate primer tRNA.
C. Barat,V. Lullien,O. Schatz,Gérard Keith,M. T. Nugeyre,F. Gruninger-Leitch,F. Barre-Sinoussi,S. F. J. Legrice,Jean-Luc Darlix +8 more
TL;DR: It is demonstrated that the HIV‐1 RT p66/p51 specifically binds to its cognate primer tRNALys,3 even in the presence of a 100‐fold molar excess of other tRNAs.
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Small finger protein of avian and murine retroviruses has nucleic acid annealing activity and positions the replication primer tRNA onto genomic RNA.
TL;DR: The present results show that finger protein p12 of Rous sarcoma virus (RSV) and p10 of murine leukaemia virus (MuLV) positions replication primer tRNA on the replication initiation site (PBS) at the 5′ end of the RNA genome.
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Initiation of Reverse Transcripion of HIV-1: Secondary Structure of the HIV-1 RNA/tRNA|rlmbopopnbop|Lys|clobop|3 (Template/Primer) Complex
TL;DR: Sequence comparison reveals that the main characteristics of the binary complex model are conserved among all HIV-1 isolates.