Gerhard Sandmann

TL;DR: Observations suggest that the threshold between the beneficial and adverse effects of some carotenoids is low and provides a strong stimulus to further understanding the functional effects of specific carOTenoids.

TL;DR: E elite inbred South African transgenic corn plants are created in which the levels of 3 vitamins were increased specifically in the endosperm through the simultaneous modification of 3 separate metabolic pathways, opening the way for the development of nutritionally complete cereals to benefit the world's poorest people.

TL;DR: The immutans (im) mutant of Arabidopsis shows a variegated phenotype comprising albino and green somatic sectors and a model in which IM function is linked to phytoene desaturation and, possibly, to the respiratory activity of the chloroplast is proposed.

TL;DR: It is succeeded in constructing an S. cerevisiae strain capable of producing high levels of β-carotene, up to 5.9 mg/g (dry weight), which was accomplished by the introduction of an additional copy of crtI and tHMG1 into carotenoid-producing yeast cells.

TL;DR: This work recovered a diverse population of transgenic plants expressing different enzyme combinations and showing distinct metabolic phenotypes that allowed them to identify and complement rate-limiting steps in the pathway and to demonstrate competition between β-carotene hydroxylase and bacterial β- carotene ketolase for substrates in 4 sequential steps of the extended pathway.