Gianluca Morroni

TL;DR: A novel resistance gene, named poxtA, encoding a protein of the antibiotic resistance (ARE) ABC-F lineage, was identified in the genome of an MRSA of clinical origin and can confer decreased susceptibility to phenicols, oxazolidinones and tetracyclines.

TL;DR: The result shows that M. beecheii honeys is an important source of bioactive compounds with relevant biological properties compared to A. mellifera honey.

TL;DR: Test for the optrA gene in 81 Enterococcus isolates from blood samples found only two positive isolates, and the genetic contexts of both genes proved capable of undergoing excision in circular form, and were completely sequenced.

TL;DR: Structural changes induced by M. beecheii honey on Staphylococcus aureus and Pseudomonas aeruginosa cells were observed suggesting that this honey has a potent antimicrobial action and may be an excellent candidate for the development of topical preparations for the treatment of infected wounds.

TL;DR: Enterococcus faecium E35048, a bloodstream isolate from Italy, was the first strain where the oxazolidinone resistance gene optrA was detected outside China, and the strain was also positive for the cfr, which could herald the possibility of a co-spread of the two genes, both involved in resistance to last resort agents such as the oxAZolidinones.