G
Gilberto De Nucci
Researcher at State University of Campinas
Publications - 303
Citations - 6533
Gilberto De Nucci is an academic researcher from State University of Campinas. The author has contributed to research in topics: Nitric oxide & High-performance liquid chromatography. The author has an hindex of 39, co-authored 285 publications receiving 6055 citations. Previous affiliations of Gilberto De Nucci include Royal College of Surgeons in Ireland & Metropolitan University.
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Journal ArticleDOI
The fate of radioiodinated endothelin-1 and endothelin-3 in the rat.
Erik Änggård,Simon Gallon,Giles Rae,Roger Thomas,Lorraine McLoughlin,Gilberto De Nucci,John R. Vane +6 more
TL;DR: Together, the results indicate a high density of ET-1 binding sites in the lung, liver, and kidney and that these organs may be important in removing circulating ET- 1, suggesting a role in cardiovascular regulation.
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Superoxide anions enhance platelet adhesion and aggregation.
TL;DR: The results indicate that O2− increase both platelet adhesion and aggregation, whereas other free radicals such as hydrogen peroxide or hydroxyl radicals are not involved.
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Kinins act on B1 or B2 receptors to release conjointly endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells.
TL;DR: It is concluded that Bk and des‐Arg9‐Bk were acting respectively on B2 and B1 bradykinin receptors, and the possible role of kinin receptors in the release of EDRF and PGI2 from endothelial cells is discussed.
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Prostaglandin E2 regulates inducible nitric oxide synthase in the murine macrophage cell line J774
Salvatore Milano,Francesco Arcoleo,Mariella Dieli,R. D'agostino,Pietro D'Agostino,Gilberto De Nucci,Enrico Cillari +6 more
TL;DR: Experiments carried out with exogenous PGE2 indicated that concentrations between 1 and 10 ng/mL are able to stimulate the expression of NOS and the release of NO, while higher concentrations (> 50 ng/ mL) are inhibitory.
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Acute inhibition of nitric oxide synthesis induces anxiolysis in the plus maze test.
Moacir Serralvo Faria,Marcelo Nicolas Muscará,Heitor Moreno,Simone A. Teixeira,H. B. Dias,Benedito Oliveira,Frederico Guilherme Graeff,Gilberto De Nucci +7 more
TL;DR: Results indicate that acute inhibition of NO synthesis decreases anxiety in rats, and this treatment is unlikely to be due to hypertension.