G
Giovanna Sersale
Researcher at University of Milan
Publications - 11
Citations - 401
Giovanna Sersale is an academic researcher from University of Milan. The author has contributed to research in topics: Cationic liposome & Reporter gene. The author has an hindex of 7, co-authored 11 publications receiving 385 citations.
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Journal ArticleDOI
Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs.
Alessandra Bragonzi,Alessandra Boletta,A. Biffi,Anna Muggia,Giovanna Sersale,S H Cheng,Claudio Bordignon,Baroukh M. Assael,Massimo Conese +8 more
TL;DR: A nonviral approach for transfecting various airway-derived cell lines in vitro showed that cationic polymers and lipids are able to transfect with high efficiency the reporter genes firefly luciferase and E. coli lacZ.
Journal ArticleDOI
The natural course and the impact of therapies of cardiac involvement in the mucopolysaccharidoses.
Vlasta Fesslova,Paola Corti,Giovanna Sersale,Attilio Rovelli,Pierluigi Russo,Savina Mannarino,Gianfranco Butera,Rossella Parini +7 more
TL;DR: Cardiac involvement was present early in more than a half of the patients identified as having mucopolysaccharidosis, and generally progressed, being more frequent and severe in the first and second types of the disease.
Journal ArticleDOI
Acute pyelonephritis as a cause of hyponatremia/hyperkalemia in young infants with urinary tract malformations
M.L. Melzi,Sophie Guez,Giovanna Sersale,Fabiola Terzi,Elena Secco,Giuseppina Marra,Amedea Silvia Tirelli,Baroukh M. Assael +7 more
TL;DR: It is concluded that a salt-losing syndrome with tubular resistance to aldosterone can occur during pyelonephritis in young infants with congenital UT malformation, that the risk diminishes considerably or disappears after 3 months of age and that in the absence ofUT malformation pyel onephritis does not cause acute sodium loss of clinical relevance.
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Mutational analysis of the HGSNAT gene in Italian patients with mucopolysaccharidosis IIIC (Sanfilippo C syndrome). Mutation in brief #959. Online.
Anthony O. Fedele,Mirella Filocamo,Maja Di Rocco,Giovanna Sersale,Torben Lübke,Paola Di Natale,Maria Pia Cosma,Andrea Ballabio +7 more
TL;DR: In this study, a group of MPS IIIC patients, who are mainly of Italian origin, have been clinically characterized and mutational analysis of the HGSNAT gene resulted in the identification of nine alleles, of which eight are novel.
Journal ArticleDOI
Restoration of bacterial killing activity of human respiratory cystic fibrosis cells through cationic vector-mediated cystic fibrosis transmembrane conductance regulator gene transfer.
Alessandra Biffi,Giovanna Sersale,Arianna Cassetti,Antonello Villa,Claudio Bordignon,Baroukh M. Assael,Massimo Conese +6 more
TL;DR: The results shown in this study might be helpful in considering cationic vectors as therapeutic nonviral vectors for transferring CFTR into human CF respiratory cells, as well as for restoring the bacterial killing activity defective in cystic fibrosis.