Giovanna Tacconi

TL;DR: CDMS is strongly associated with CCSVI, a scenario that has not previously been described, characterised by abnormal venous haemodynamics determined by extracranial multiple venous strictures of unknown origin.

TL;DR: A significant impairment of cerebral venous drainage in patients affected by MS is demonstrated, a mechanism potentially related to increased iron stores, when compared to revised McDonald criteria as a gold standard of MS diagnosis.

TL;DR: This study of MS patients demonstrated significant haemodynamic alterations detected in veins anatomically related to plaque disposition, which should contribute towards understanding the role of altered venous flow and tissue drainage in the MS inflammatory chain, as well as in the neurodegenerative process.

TL;DR: The complex gross and radiological anatomy of collateral circulation found activated by the means of EchoColor-Doppler and selective venography in the event of CCSVI is reviewed, focusing particularly on the suboccipital cavernous sinus (SCS), the condylar venous system, the pterygoid plexus, the thyroid veins, and the emiazygous-lumbary venous anastomosis.

TL;DR: By analyzing simultaneously selected SNPs in candidate genes involved in VLU to identify potentially prognostic markers by means of DNA-array technology, it might be possible to glean precious information in predicting VLU onset or in stratifying patients according to their potential to heal.