G
Giovanni Giac. Rovera
Researcher at University of Turin
Publications - 36
Citations - 2546
Giovanni Giac. Rovera is an academic researcher from University of Turin. The author has contributed to research in topics: Antigen & Leukemia. The author has an hindex of 18, co-authored 36 publications receiving 2525 citations.
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Journal ArticleDOI
Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.
TL;DR: Data indicate that, after treatment with TPA, human promyelocytic leukemia cells can differentiate into cells that have several characteristics of macrophages.
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A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia
Luigi Pegoraro,Antonio Palumbo,Jan Erikson,Michele Falda,Bruna Giovanazzo,Beverly S. Emanuel,Giovanni Giac. Rovera,Peter C. Nowell,Carlo M. Croce +8 more
TL;DR: A model of some aspects of B-cell oncogenesis is proposed according to which B- cell neoplasms carrying translocations involving the heavy chain loci on both human chromosomes 14 are the result of a multiple step process.
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Tumor promoters inhibit spontaneous differentiation of Friend erythroleukemia cells in culture
TL;DR: Clones of Friend erythroleukemia cells, characterized by the presence of 40-70% benzidine-positive cells synthesizing hemoglobin in the absence of inducing drugs, were treated with several phorbol diesters with a known range of tumor-promoting activity on mouse skin and retained a high potential for spontaneous differentiation.
Journal Article
Differential Expression of the Globin Genes in Human Leukemia K562(S) Cells Induced to Differentiate by Hemin or Butyric Acid
Livia Cioe,Alistair McNab,Howard R. Hubbell,Pacifico Meo,Peter J. Curtis,Giovanni Giac. Rovera +5 more
TL;DR: Analysis of the globin chains in induced K562(S) cells induced to differentiate indicated that, with both inducers, adult alpha- but not beta-globin chains were present, and indicates that hemin and butyric acid differ in their effects on the expression of embryonal globin genes.
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Anger and personality in eating disorders.
TL;DR: Clinically, impulsivity seems to be the psychopathologic element most strongly correlated to anger, and it appears clear that anger is better managed by individuals with greater character strength.