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Giulia Chiesa
Researcher at University of Milan
Publications - 103
Citations - 4660
Giulia Chiesa is an academic researcher from University of Milan. The author has contributed to research in topics: Cholesterol & Apolipoprotein B. The author has an hindex of 32, co-authored 96 publications receiving 4368 citations. Previous affiliations of Giulia Chiesa include University of Havana & Lawrence Berkeley National Laboratory.
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Apolipoprotein(a) gene accounts for greater than 90 % of the variation in plasma lipoprotein(a) concentrations
TL;DR: The apo(a) gene itself was found to account for virtually all the genetic variability in plasma Lp(a), a low density lipoprotein particle with an attached apolipoprotein (a) that varies widely in concentration between individuals.
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Atherogenesis in transgenic mice expressing human apolipoprotein( a )
TL;DR: It is shown that transgenic mice expressing human apolipoprotein(a) are more susceptible than control mice to the development of lipid-staining lesions in the aorta, and that Apolipop protein co-localizes with lipid deposition in the artery walls.
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Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).
MacRae F. Linton,Robert V. Farese,Giulia Chiesa,David S. Grass,Peter Chin,Robert E. Hammer,Helen H. Hobbs,Stephen G. Young +7 more
TL;DR: Both the human apo-B and Lp(a) transgenic mice will be valuable resources for studying apo’B metabolism and the role of apo (a), Lp (a) in atherosclerosis.
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Recombinant Apolipoprotein A-IMilano Infusion Into Rabbit Carotid Artery Rapidly Removes Lipid From Fatty Streaks
Giulia Chiesa,Elena Monteggia,Marta Marchesi,P. Lorenzon,Massimo Laucello,Vito Lorusso,Carlo Di Mario,Evangelia Karvouni,Roger S. Newton,Charles L. Bisgaier,Guido Franceschini,Cesare R. Sirtori +11 more
TL;DR: Results suggest AIM-PL complexes enhanced lipid removal from arteries is the mechanism responsible for the observed plaque changes.
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Reconstitution of lipoprotein(a) by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein(a).
Giulia Chiesa,Helen H. Hobbs,Marlys L. Koschinsky,Richard M. Lawn,Shanna D. Maika,Robert E. Hammer +5 more
TL;DR: It is suggested that apo(a) fails to associate with mouse lipoproteins due to structural differences between human and mouse LDL, and that Lp(a), formation can occur in plasma through the association of apo (a) with circulating LDL.