G
Giulia Grizzi
Researcher at University of Verona
Publications - 18
Citations - 286
Giulia Grizzi is an academic researcher from University of Verona. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 12 publications receiving 190 citations. Previous affiliations of Giulia Grizzi include University of Modena and Reggio Emilia.
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Journal ArticleDOI
Immune-related Adverse Events and Survival in Solid Tumors Treated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis
Fausto Petrelli,Giulia Grizzi,Michele Ghidini,Antonio Ghidini,Margherita Ratti,Stefano Panni,Mary Cabiddu,Mara Ghilardi,Karen Borgonovo,Maria Chiara Parati,Gianluca Tomasello,Sandro Barni,Alfredo Berruti,Matteo Brighenti +13 more
TL;DR: In patients treated with ICIs, irAEs predict survival and response, and although this correlation cannot be fully explained, it may be related to the strongest T-cell activation.
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Do immune checkpoint inhibitors need new studies methodology
Roberto Ferrara,Sara Pilotto,Mario Caccese,Giulia Grizzi,Isabella Sperduti,Diana Giannarelli,Michele Milella,Benjamin Besse,Giampaolo Tortora,Emilio Bria +9 more
TL;DR: Developing original and high-quality study designs, such as adaptive or basket biomarker enriched clinical trials, included in large collaborative platforms with multiple active sites and cross-sector collaboration, represents the successful strategy to optimally assess the benefit of ICI in the next future.
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Resistance to EGFR inhibitors in non-small cell lung cancer: Clinical management and future perspectives.
Chiara Tomasello,Cinzia Baldessari,Martina Napolitano,Giulia Orsi,Giulia Grizzi,Federica Bertolini,Fausto Barbieri,Stefano Cascinu +7 more
TL;DR: The molecular alterations underlying each of these EGFR TKIs resistance mechanisms are described, focusing on the currently available and future therapeutic strategies to overcome these phenomena.
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Nivolumab-Induced Impressive Response of Refractory Pulmonary Sarcomatoid Carcinoma with Brain Metastasis
Massimiliano Salati,Cinzia Baldessari,Fiorella Calabrese,Giulio Rossi,Elisa Pettorelli,Giulia Grizzi,Massimo Dominici,Fausto Barbieri +7 more
TL;DR: In very lethal non-small cell lung cancer subtypes such as the sarcomatoid variants, high tumor burden and deteriorated general conditions should not preclude, at least in some cases, the use of immunotherapy.
Journal ArticleDOI
Putative predictors of efficacy for immune checkpoint inhibitors in non-small-cell lung cancer: facing the complexity of the immune system.
Giulia Grizzi,Mario Caccese,A. Gkountakos,Luisa Carbognin,Giampaolo Tortora,Emilio Bria,Sara Pilotto +6 more
TL;DR: This analysis aims to review the main findings about predictive biomarkers for immunotherapy in lung cancer, retracing the history of PD-L1 and focusing on a series of innovative candidates, such as mutational load, immune cell populations and microbiome.