G
Giuliano Ramadori
Researcher at University of Göttingen
Publications - 347
Citations - 15257
Giuliano Ramadori is an academic researcher from University of Göttingen. The author has contributed to research in topics: Hepatic stellate cell & Gene expression. The author has an hindex of 60, co-authored 344 publications receiving 14521 citations. Previous affiliations of Giuliano Ramadori include University of Mainz.
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Journal ArticleDOI
One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial.
Heikki Joensuu,Mikael Eriksson,Kirsten Sundby Hall,Jörg T. Hartmann,Daniel Pink,Jochen Schütte,Giuliano Ramadori,Peter Hohenberger,Justus Duyster,Salah-Eddin Al-Batran,Marcus Schlemmer,Sebastian Bauer,Eva Wardelmann,Maarit Sarlomo-Rikala,Bengt Nilsson,Harri Sihto,Odd R. Monge,Petri Bono,Raija Kallio,Aki Vehtari,M. Leinonen,Thor Alvegård,Peter Reichardt +22 more
TL;DR: Adjuvant imatinib administered for 12 months after surgery has improved recurrence-free survival (RFS) of patients with operable gastrointestinal stromal tumor (GIST) compared with placebo and overall survival of GIST patients with a high risk of Gist recurrence.
One vs Three Years of Adjuvant Imatinib for Operable Gastrointestinal Stromal Tumor
Journal ArticleDOI
Gene regulation of heme oxygenase-1 as a therapeutic target
TL;DR: Models of experimental injuries are highlighted in which specific overexpression of the HO-1 gene either by targeted gene transfer or by pharmacological modulation has been demonstrated to provide therapeutic effects.
Journal Article
Rat liver myofibroblasts and hepatic stellate cells : different cell populations of the fibroblast lineage with fibrogenic potential
Thomas Knittel,Dominik Kobold,Bernhard Saile,Anka Grundmann,Katrin Neubauer,Fabio Piscaglia,Giuliano Ramadori +6 more
TL;DR: In this article, the authors established cultures of cells of the fibroblast lineage, termed rat liver myofibroblasts, and analyzed their phenotypical and functional properties in comparison with HSCs.
Journal ArticleDOI
Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-α and TGF-β1
TL;DR: All resident liver cells are involved in matrix degradation to some extent and that hepatic stellate cells play an important role in matrix breakdown in addition to matrix synthesis, as demonstrated by reverse transcription-polymerase chain reaction and zymography.