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Giuseppe Pontrelli

Researcher at Boston Children's Hospital

Publications -  136
Citations -  2859

Giuseppe Pontrelli is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Lattice Boltzmann methods & Drug delivery. The author has an hindex of 27, co-authored 121 publications receiving 2255 citations. Previous affiliations of Giuseppe Pontrelli include University of Bari & Istituto Superiore di Sanità.

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Biomimetic Nanotherapies: Red Blood Cell Based Core-Shell Structured Nanocomplexes for Atherosclerosis Management.

TL;DR: This study demonstrates the therapeutic advantages of biomimetic nanotherapy for Atherosclerosis treatment, which holds considerable promise as a new generation of drug delivery system for safe and efficient management of atherosclerosis.
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Macrophage membrane functionalized biomimetic nanoparticles for targeted anti-atherosclerosis applications.

TL;DR: It is demonstrated that MM/RAPNPs could efficiently and safely inhibit the progression of AS and may be potential drug delivery systems for safe and effective anti-AS applications.
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Mass diffusion through two-layer porous media: an application to the drug-eluting stent

TL;DR: In this paper, a mathematical model for the diffusion-transport of a substance between two porous homogeneous media of different properties and dimensions is presented and a strong analogy with the one-dimensional transient heat conduction process across two-layered slabs is shown and a similar methodology of solution is proposed.
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A multi-layer porous wall model for coronary drug-eluting stents

TL;DR: An analytical solution for solving the transient drug diffusion in adjoining porous wall layers faced with a drug-eluting stent is presented in this article, where the endothelium, intima, internal elastic lamina and media are all treated as homogeneous porous media and the drug transfer through them is modelled by a set of coupled partial differential equations.