G
Giusy Comito
Researcher at University of Florence
Publications - 1
Citations - 143
Giusy Comito is an academic researcher from University of Florence. The author has contributed to research in topics: Cell migration & Platelet-derived growth factor receptor. The author has an hindex of 1, co-authored 1 publications receiving 134 citations.
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Proliferation versus migration in platelet-derived growth factor signaling: the key role of endocytosis.
Alina De Donatis,Giusy Comito,Francesca Buricchi,Maria Cristina Vinci,Astrid Parenti,Anna Caselli,Guido Camici,Giampaolo Manao,Giampietro Ramponi,Paolo Cirri +9 more
TL;DR: The results suggest a mechanism by which cells switch from a migrating to a proliferating phenotype sensing the increasing gradient of PDGF, and propose that the cell decision to proliferate or migrate relies on different endocytotic routes of the PDGF receptor in response to different PDGF concentrations.