G
Glen Stevens
Researcher at Cleveland Clinic
Publications - 83
Citations - 2826
Glen Stevens is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Temozolomide & Radiation therapy. The author has an hindex of 25, co-authored 72 publications receiving 2413 citations. Previous affiliations of Glen Stevens include Cleveland Clinic Lerner College of Medicine.
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Journal ArticleDOI
Serum S100β: A Noninvasive Marker of Blood-Brain Barrier Function and Brain Lesions
Andrew A. Kanner,Andrew A. Kanner,Nicola Marchi,Vincent Fazio,Marc R. Mayberg,Marc R. Mayberg,Michael T. Koltz,Vitaly Siomin,Glen Stevens,Thomas J. Masaryk,Barbara Ayumar,Michael A. Vogelbaum,Gene H. Barnett,Damir Janigro +13 more
TL;DR: It remains unclear whether elevation of serum levels of S100β reflect BBB dysfunction, parenchymal damage, or both, after head trauma, subarachnoid hemorrhage, and stroke.
Journal ArticleDOI
Challenges With the Diagnosis and Treatment of Cerebral Radiation Necrosis
Samuel T. Chao,Manmeet Ahluwalia,Gene H. Barnett,Glen Stevens,Erin S. Murphy,Abigail L. Stockham,Kevin Shiue,John H. Suh +7 more
TL;DR: The incidence of radiation necrosis has increased secondary to greater use of combined modality therapy for brain tumors and stereotactic radiosurgery, and a recent prospective randomized study has confirmed the efficacy of bevacizumab in treating Radiation necrosis.
Journal ArticleDOI
Blood-Brain Barrier Disruption and Intra-Arterial Methotrexate-Based Therapy for Newly Diagnosed Primary CNS Lymphoma: A Multi-Institutional Experience
Lilyana Angelov,Nancy D. Doolittle,Dale F. Kraemer,Tali Siegal,Gene H. Barnett,David M. Peereboom,Glen Stevens,John M. McGregor,Kristoph Jahnke,Cynthia Lacy,Nancy A. Hedrick,Edna Shalom,S. Ference,Sue E. Bell,Lisa Sorenson,Rose Marie Tyson,Marianne Haluska,Edward A. Neuwelt +17 more
TL;DR: This large series of patients treated over a 23-year period demonstrates that BBBD/IA methotrexate-based chemotherapy results in successful and durable tumor control and outcomes that are comparable or superior to other PCNSL treatment regimens.
Journal ArticleDOI
Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme
David M. Peereboom,Dale R. Shepard,Manmeet Ahluwalia,Cathy Brewer,Neeraj Agarwal,Glen Stevens,John H. Suh,Steven A. Toms,Michael A. Vogelbaum,Robert J. Weil,Paul Elson,Gene H. Barnett +11 more
TL;DR: This phase 2 study assessed the efficacy and safety of concurrent radiation therapy and temozolomide with pharmacodynamic dose escalation of erlotinib in patients with newly diagnosed glioblastomas and terminated after accrual of 27 of 30 planned patients.
Journal Article
T cell adoptive immunotherapy of newly diagnosed gliomas.
Gregory E. Plautz,David W. Miller,Gene H. Barnett,Glen Stevens,Scott Maffett,Julian Kim,Peter A. Cohen,Suyu Shu +7 more
TL;DR: This Phase I clinical trial of adoptive immunotherapy for patients with newly diagnosed malignant gliomas demonstrates feasibility, lack of long-term toxicity, and several objective clinical responses.