Showing papers by "Glenn M. Sammis published in 2013"
TL;DR: The potential-controlled incorporation of DOPC liposomes into an adsorbed octadecanol layer on Au(111) was studied and the extent of fluorescence changes was found to be strongly dependent on the nature of the advertisersorbed layer under investigation, which suggests that the poration and liposome interaction are dependent onThe quality of the adsorBed layer and its ease of poration through changes in the electrode potential.
Abstract: The potential-controlled incorporation of DOPC liposomes (100 nm diameter) into an adsorbed octadecanol layer on Au(111) was studied using electrochemical and in situ fluorescence microscopy. The adsorbed layer of octadecanol included a small amount of a lipophilic fluorophore—octadecanol modified with BODIPY—to enable fluorescence imaging. The deposited octadecanol layer was found not to allow liposomes to interact unless the potential was less than −0.4 V/SCE, which introduces defects into the adsorbed layer. Small increases in the capacitance of the adsorbed layer were measured after introducing the defects, allowing the liposomes to interact with the defects and then annealing the defects at 0 V/SCE. A change in the adsorbed layer was also signified by a more positive desorption potential for the liposome-modified adsorbed layer as compared to that for an adsorbed layer that was porated in a similar fashion but without liposomes present in the electrolyte. These subtle changes in capacitance are diffi...
8 citations
TL;DR: In this article, photolysis of the title compounds in the presence of Selectfluor results in decarboxylative fluorination to afford fluoromethyl ethers and benzyl fluorides.
Abstract: Photolysis of the title compounds in the presence of Selectfluor results in decarboxylative fluorination to afford fluoromethyl ethers and benzyl fluorides.
1 citations