Gloria del Solar

TL;DR: Most of the current knowledge on plasmid replication and its control is based on the results of analyses performed with pure cultures under steady-state growth conditions, and sets important parameters needed to understand the maintenance of these genetic elements in mixed populations and under environmental conditions.

TL;DR: Bacterial plasmids maintain their number of copies by negative regulatory systems that adjust the rate of replication per plasmid copy in response to fluctuations in the copy number, and exciting insights have been obtained on the molecular basis of the inhibition mechanism that prevents the formation of a long‐range RNA structure.

TL;DR: The structure of the 45 amino acid transcriptional repressor, CopG, has been solved unliganded and bound to its target operator DNA, and it is revealed that the bihelical region of CopG has a role in oligomerization instead of DNA recognition.

TL;DR: Computer assisted analysis showed that the signal detected in pLS1 has a high degree of homology with the complementary strand origin of the Escherichia coli single stranded bacteriophages phi X174 and M13.

TL;DR: This is the first dissected example of a transcription factor functioning as a phosphorylation-activated switch for a cold-shock gene, allowing the cell to optimize the fluidity of membrane phospholipids.