G
Gonçalo C. Justino
Researcher at Instituto Superior Técnico
Publications - 36
Citations - 1072
Gonçalo C. Justino is an academic researcher from Instituto Superior Técnico. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 12, co-authored 26 publications receiving 905 citations. Previous affiliations of Gonçalo C. Justino include Instituto Politécnico Nacional & University of Lisbon.
Papers
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Journal ArticleDOI
Structure-antioxidant activity relationships of flavonoids: a re-examination.
TL;DR: It was found that these three flavonoids exhibited comparable antioxidant activities against different oxidants leading to the conclusion that the presence of ortho -catechol group (3',4'-OH) in the B-ring is determinant for a high antioxidant capacity.
Journal ArticleDOI
Plasma quercetin metabolites: structure-antioxidant activity relationships.
Gonçalo C. Justino,Marta R. Santos,Sónia Canário,Carlos Borges,M. Helena Florêncio,Lurdes Mira +5 more
TL;DR: Results enabled the establishment of quercetin metabolite structure-antioxidant activity relationships and, hence, to understand their contribution for the antioxidant potential of plasma.
Journal ArticleDOI
Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy.
Inês L. Martins,Catarina Charneira,Valentina Gandin,João L. Ferreira da Silva,Gonçalo C. Justino,João P. Telo,Abel J. S. C. Vieira,Cristina Marzano,Alexandra M. M. Antunes +8 more
TL;DR: The preliminary investigation on the mechanism of cytotoxicity of SeChry and SePQue in MCF-7 human mammary cancer cells demonstrated their capacity to efficiently suppress the clonal expansion along with their ability to hamper TrxR activity leading to apoptotic cell death.
Book ChapterDOI
Structural Analysis of Flavonoids and Related Compounds - A Review of Spectroscopic Applications
TL;DR: In the early 90s and early 00s the metabolism of flavonoids was deeply scrutinized, and the results indicated that their antioxidant activity in vivo could not account for the overall actions attributed to them.