Showing papers by "Gordon L. Warren published in 2015"

Aging and the Muscle-Bone Relationship

Abstract: Aging-induced declines in muscle size and quality are thought to contribute to catabolic alterations in bone, but changes in bone with age also profoundly alter its response to muscle-derived stimuli. This review provides an overview of some of the alterations that occur in muscle and bone with aging, and discusses the cellular and molecular mechanisms that may impact these age-associated changes.

Clinical Measures Predicting Knee Extensor Muscle Activation During a Maximal Voluntary Isometric Contraction

Abstract: fiber pennation angle) but also by its neurophysiological properties (e.g., motor unit recruitment, rate coding, motor unit synchronization). Several studies have shown that the deficits in knee extensor strength found after knee injuries are attributable more to decreased knee extensor muscle activation than to muscle atrophy due to disuse [1-3]. The inability to maximally activate the knee extensors in the absence of frank tissue damage can alter athletic performance, which often relies on optimal contraction of this lower-extremity muscle group [1].

Addition of hip exercises to treatment of patellofemoral pain syndrome: A meta-analysis

Abstract: AIM: To determine if the addition of hip-strengthening exercises decreases pain and improves function in patients with patellofemoral pain syndrome. METHODS: The authors completed a systematic review searching eight databases (i.e., PubMed, Cochrane, CINHAL, MEDLINE, SportsDiscus, EMBASE, APTA Hooked on Evidence, and PEDro). Two independent reviewers screened and excluded studies if they did not meet the following inclusion criteria: subjects had a primary diagnosis of patellofemoral pain syndrome (PFPS), intervention group included hip-strengthening exercises, control group included a traditional physical therapy intervention, study included outcome measures of pain and/or function, study used a randomized controlled trial design, PEDro score was ≥ 7, and study was published in a peer-reviewed journal. Primary outcome measures were subjective scales of pain and function. These measures were converted to standardized mean difference [effect size (ES)], and a random-effects model was used to calculate the overall ES.

Estradiol enhances neutrophil infiltration into traumatically-injured skeletal muscle

Abstract: Purpose: To probe how estradiol modulates neutrophil infiltration and function following traumatic muscle injury Methods: Adult, female C57BL/6 mice were ovariectomized and randomly assigned to no