Grant K. Nation

TL;DR: It is established that tau expression differentially shifts both the transcriptome and the nascent proteome, and that the synthesis of ribosomal proteins is reversibly dependent on tau levels, which establishes tau as a driver of RNA translation selectivity.

TL;DR: A manganese-enhanced magnetic resonance imaging approach is modified and adapted to provide sensitive and quantitative power to detect changes in broad neuronal function in aging mice and represents the first diagnostic measure of neuronal dysfunction in mice.

TL;DR: Evidence is provided that repetitive TBIs can result in worse and more persistent neurological deficits compared to a single TBI, but the direct link between the worsened outcome and elevated p-tau could not be established.

TL;DR: A simple, minimally-invasive and cost-effective method of tracer delivery to study SIRM in vivo in laboratory mice and resolves significant differences in multiple central carbon pathways in both model systems, providing evidence of the utility of this method to study diseases with metabolic components.

TL;DR: Although this gene flow is likely to be historical rather than current, the existence of recent gene flow between these two genetically divergent species reinforces the importance of premating barriers in the process of speciation.