Gregory W. Aponte

TL;DR: An immunohistochemical study was conducted to detect the temporal infection sequence of Autographa californica M nuclear polyhedrosis virus in Trichoplusia ni larvae and stained patterns indicated that the initial infection occurred in the midgut, simultaneously in columnar epithelial and regenerative cells, but that subsequently this tissue recovered.

TL;DR: PAR-2-mediated Ca2+ mobilization desensitizes by irreversible receptor cleavage, protein kinase C-mediated termination of signaling, and PAR-2 targeting to lysosomes and resensitized by mobilization of large Golgi stores and synthesis of new receptors.

TL;DR: In this article, peptide hormones were used as affinity ligands to purify a set of 25-kilodalton proteins from canine pancreatic tissue and their ligand specificities and patterns of expression have the characteristics of sorting carriers.

TL;DR: This study implicates the nuclear-cytoplasmic shuttling of sgk as a requirement for cell cycle progression and represents a novel convergence point of anti-proliferative and proliferative signaling in mammary tumor cells.

TL;DR: The data indicate that GPR93 can contribute to the observed induction of CCK expression and secretion by peptone and provide evidence that G protein-coupled receptors can transduce dietary luminal signals.