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Greta Dreyer
Researcher at University of Pretoria
Publications - 71
Citations - 893
Greta Dreyer is an academic researcher from University of Pretoria. The author has contributed to research in topics: Cervical cancer & Population. The author has an hindex of 14, co-authored 59 publications receiving 691 citations.
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Journal ArticleDOI
Human papillomavirus prevalence and type distribution in invasive cervical cancer in sub-Saharan Africa.
Lynette Denny,Isaac F. Adewole,Rose I Anorlu,Greta Dreyer,Manivasan Moodley,Trudy Smith,Leon Cornelius Snyman,Edwin K. Wiredu,Anco Molijn,Wim Quint,Gunasekaran Ramakrishnan,Johannes E. Schmidt +11 more
TL;DR: HPV16, 18, 45 and 35 were the most common HPV types in sub‐Saharan African women with ICC and HPV infections were more common in HIV‐positive women.
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BRCA1 mutations in South African breast and/or ovarian cancer families: Evidence of a novel founder mutation in Afrikaner families
Michelle D. Reeves,Tali M. Yawitch,Nerina C. van der Merwe,Hester Js van den Berg,Greta Dreyer,Elizabeth J. van Rensburg +5 more
TL;DR: Of the remaining mutations detected, 3 have not been reported previously and include the S451X, 1493delC (detected twice) and 4957insC mutations, which include the E881X mutation, which is believed to have originated in France in the late 1600s.
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Age-specific prevalence of cervical human papillomavirus infection and cytological abnormalities in women in Gauteng Province, South Africa
TL;DR: The prevalences of HPV infection and abnormal cytology were much higher than previously reported in general populations in South Africa and elsewhere and have implications for planning and development of cervical screening programmes in developing countries with largely unscreened populations with a high background prevalence of HIV.
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PTEN mutations in uterine sarcomas.
Frédéric Amant,M de la Rey,Cecelia M Dorfling,L. van der Walt,Greta Dreyer,L Dreyer,Ignace Vergote,B. G. Lindeque,E. J. Van Rensburg +8 more
TL;DR: In this article, the authors investigated the role of the PTEN tumor suppressor gene in the pathogenesis of the endometrioid type of endometrial carcinoma and found that 8.5% (4/47) of uterine leiomyosarcoma were found to harbor somatic PTEN mutations.
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Cost effectiveness of high-risk HPV DNA testing for cervical cancer screening in South Africa.
TL;DR: In a lifetime Markov model of the costs, quality of life, and survival associated with screening and treating cervical cancer and its precursors in South Africa, HPV testing to screen for cervical cancers is a cost-effective strategy.