Greta Dreyer

TL;DR: HPV16, 18, 45 and 35 were the most common HPV types in sub‐Saharan African women with ICC and HPV infections were more common in HIV‐positive women.

TL;DR: Of the remaining mutations detected, 3 have not been reported previously and include the S451X, 1493delC (detected twice) and 4957insC mutations, which include the E881X mutation, which is believed to have originated in France in the late 1600s.

TL;DR: The prevalences of HPV infection and abnormal cytology were much higher than previously reported in general populations in South Africa and elsewhere and have implications for planning and development of cervical screening programmes in developing countries with largely unscreened populations with a high background prevalence of HIV.

TL;DR: In this article, the authors investigated the role of the PTEN tumor suppressor gene in the pathogenesis of the endometrioid type of endometrial carcinoma and found that 8.5% (4/47) of uterine leiomyosarcoma were found to harbor somatic PTEN mutations.

TL;DR: In a lifetime Markov model of the costs, quality of life, and survival associated with screening and treating cervical cancer and its precursors in South Africa, HPV testing to screen for cervical cancers is a cost-effective strategy.