G
Guang Yang
Researcher at Torrey Pines Institute for Molecular Studies
Publications - 4
Citations - 625
Guang Yang is an academic researcher from Torrey Pines Institute for Molecular Studies. The author has contributed to research in topics: Adipose tissue & Insulin resistance. The author has an hindex of 4, co-authored 4 publications receiving 584 citations.
Papers
More filters
Journal ArticleDOI
Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome
Guang Yang,Leylla Badeanlou,Jacek Bielawski,Amanda J. Roberts,Yususf A Hannun,Fahumiya Samad +5 more
TL;DR: A novel role for ceramide biosynthesis in body weight regulation, energy expenditure, and the metabolic syndrome is highlighted.
Journal ArticleDOI
Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1.
TL;DR: A novel link between sphingolipid metabolism and PAI-1 is identified and it is suggested that ceramide may be an intermediary molecule linking elevated PAi-1 to insulin resistance.
Journal ArticleDOI
Tissue factor–protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation
TL;DR: In hematopoietic cells, genetic ablation of tissue factor–PAR2 signaling reduced adipose tissue Macrophage inflammation, and specific pharmacological inhibition of macrophage tissue factor signaling rapidly ameliorated insulin resistance.
Book ChapterDOI
Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity.
TL;DR: This chapter will focus primarily on the expression and regulation of adipose and plasma ceramide biosynthesis in obesity and, its potential contribution to the pathogenesis of obesity and the metabolic syndrome.