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Guido Romano

Researcher at University of Catania

Publications -  34
Citations -  623

Guido Romano is an academic researcher from University of Catania. The author has contributed to research in topics: Poison control & Principal component analysis. The author has an hindex of 14, co-authored 34 publications receiving 555 citations.

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Hair testing for drugs of abuse: evaluation of external cocaine contamination and risk of false positives

TL;DR: The aim of the present study is to verify if a single external contamination with a small amount of cocaine will last sufficiently long to make a contaminated subject indistinguishable from active users, and if normal washing practices together with the decontamination procedures are sufficient to completely remove the external contamination.
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Determination of drugs of abuse in hair: evaluation of external heroin contamination and risk of false positives.

TL;DR: The results suggest that decontamination procedures are not sufficient to remove drugs penetrated into hair from external source, and all contaminated subjects were positive for opiates for at least 3 months.
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Determination of GHB in human hair by HPLC-MS/MS: Development and validation of a method and application to a study group and three possible single exposure cases.

TL;DR: A method for the detection of GHB in human hair by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) after liquid-liquid extraction (LLE) was developed and fully validated and applied to three real cases where a GHB single exposure probably occurred.
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Qualitative organic analysis. I. Identification of drugs by principal components analysis of standardized thin-layer chromatographic data in four eluent systems.

TL;DR: In this article, principal component analysis of standardized R F values in four eluent systems [ethyl] acetate,methanol,30% ammonia (85:10:15), cyclohexane,toluene-diethylamine (65:25:10), ethyl acetate-chloroform (50:50) and acetone, with the plate dipped in potassium hydroxide solution] provided a two-component model which accounts for 73% of the total variance.
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Post mortem concentrations of endogenous gamma hydroxybutyric acid (GHB) and in vitro formation in stored blood and urine samples

TL;DR: The findings allow us to affirm that the PMI strongly affects the post mortem production of GHB in blood and urine samples and recommend the latter as optimal storage temperature.