G
Guilherme Venâncio Símaro
Researcher at University of São Paulo
Publications - 13
Citations - 168
Guilherme Venâncio Símaro is an academic researcher from University of São Paulo. The author has contributed to research in topics: Piper cubeba & Antibacterial activity. The author has an hindex of 7, co-authored 13 publications receiving 129 citations.
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Journal ArticleDOI
In vitro efficacy of the essential oil of Piper cubeba L.(Piperaceae) against Schistosoma mansoni
Lizandra Guidi Magalhães,Julia Medeiros Souza,Kamila A. L. Wakabayashi,Rosangela da Silva de Laurentiz,A. H. C. Vinhólis,Karen Cristina Souza Rezende,Guilherme Venâncio Símaro,Jairo Kenupp Bastos,Vanderlei Rodrigues,Viviane Rodrigues Esperandim,Daniele da Silva Ferreira,Antônio Eduardo Miller Crotti,Wilson Roberto Cunha,Márcio Luis Andrade e Silva +13 more
TL;DR: The results suggest that PC-EO possesses an effect against cercariae, schistosomula, and adult worms of the S. mansoni.
Journal ArticleDOI
In vitro antiparasitic activity and chemical composition of the essential oil obtained from the fruits of Piper cubeba.
Viviane Rodrigues Esperandim,Daniele da Silva Ferreira,Karen Cristina Sousa Rezende,Lizandra Guidi Magalhães,Julia Medeiros Souza,Patrícia Mendonça Pauletti,Ana Helena Januário,Rosangela da Silva de Laurentz,Jairo Kenupp Bastos,Guilherme Venâncio Símaro,Wilson Roberto Cunha,Márcio Luis Andrade e Silva +11 more
TL;DR: The essential oil reported that the essential oil obtained by steam distillation of the fruits of Piper cubeba is active against Schistosoma mansoni is investigated to determine the compounds responsible for the observed activities, as well as its mechanism of action.
Journal ArticleDOI
Antibacterial activity of (-)-cubebin isolated from Piper cubeba and its semisynthetic derivatives against microorganisms that cause endodontic infections
Karen Cristina Sousa Rezende,Rodrigo Lucarini,Guilherme Venâncio Símaro,Patrícia Mendonça Pauletti,Ana Helena Januário,Viviane Rodrigues Esperandim,Carlos Henrique Gomes Martins,Mislaine A Silva,Wilson Roberto Cunha,Jairo Kenupp Bastos,Márcio Luis Andrade e Silva +10 more
TL;DR: Cytotoxicity assays demonstrated that (1) and its derivatives do not display toxicity and the relationship between structure and antimicrobial activity of derivatives against microorganisms that cause endodontic infections is analyzed.
Journal ArticleDOI
In vivo and in silico anti-inflammatory mechanism of action of the semisynthetic (-)-cubebin derivatives (-)-hinokinin and (-)-O-benzylcubebin.
Thais C. Lima,Rodrigo Lucarini,Angélica Campos Cintra Volpe,Carolina Quireza Jacob de Andrade,Alice Monique Pacheco Souza,Patrícia Mendonça Pauletti,Ana Helena Januário,Guilherme Venâncio Símaro,Jairo Kenupp Bastos,Wilson Roberto Cunha,Alexandre Luiz Souto Borges,Rosangela da Silva Laurentiz,Valéria A. Conforti,Renato L. T. Parreira,Carly Henrique Gambeta Borges,Giovanni F. Caramori,Karla F. Andriani,Márcio Luis Andrade e Silva +17 more
TL;DR: Using paw edema as the experimental model and different chemical mediators (prostaglandin and dextran), it was observed that both derivatives were active in comparison with both negative (5% Tween® 80 in saline) and positive (indomethacin) controls.
Journal ArticleDOI
(−)-Hinokinin Induces G2/M Arrest and Contributes to the Antiproliferative Effects of Doxorubicin in Breast Cancer Cells
Nayanne Larissa Cunha,Gabriella Machado Teixeira,Thomás Duzzi Martins,Anderson Roberto de Souza,Pollyana Francieli Oliveira,Guilherme Venâncio Símaro,Karen Cristina Souza Rezende,Natália dos Santos Gonçalves,Daniel Gottardo Souza,Denise Crispim Tavares,Márcio Luis Andrade e Silva,Raquel Alves dos Santos +11 more
TL;DR: The findings of the present study suggest (-)-hinokinin as an antiproliferative agent that contributes to the effects of doxorubicin.