G
Guirong Wang
Researcher at State University of New York Upstate Medical University
Publications - 92
Citations - 3138
Guirong Wang is an academic researcher from State University of New York Upstate Medical University. The author has contributed to research in topics: Surfactant protein A & Gene. The author has an hindex of 29, co-authored 83 publications receiving 2793 citations. Previous affiliations of Guirong Wang include Pennsylvania State University.
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Journal ArticleDOI
Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis
Moisés Selman,Hung Mo Lin,Martha Montaño,Audrey L. Jenkins,Andrea Estrada,Zhenwu Lin,Guirong Wang,Susan L. DiAngelo,Xiaoxuan Guo,Todd M. Umstead,C. Max Lang,Annie Pardo,David S. Phelps,Joanna Floros +13 more
TL;DR: Findings indicate that surfactant protein variants may serve as markers to identify subgroups of patients at risk, and speculate that these contribute to IPF pathogenesis.
Journal ArticleDOI
Novel, Non-Radioactive, Simple and Multiplex PCR-cRFLP Methods for Genotyping Human SP-A and SP-D Marker Alleles
Susan L. DiAngelo,Zhenwu Lin,Guirong Wang,Scott T. Phillips,Mika Rämet,Junming Luo,Joanna Floros +6 more
TL;DR: It has been determined that SP-D shares similar roles in immune response and the ability to more accurately and efficiently genotype samples from individuals with various pulmonary diseases will facilitate population and family based association studies.
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Surfactant protein gene A, B, and D marker alleles in chronic obstructive pulmonary disease of a Mexican population
Xiaoxuan Guo,Hung Mo Lin,Zhenwu Lin,M M Montaño,R Sansores,Guirong Wang,Susan L. DiAngelo,A Pardo,M Selman,Joanna Floros +9 more
TL;DR: The present results indicate that the surfactant protein alleles may be useful in chronic obstructive pulmonary disease by either predicting the disease in a subgroup and/or by identifying disease subgroups that may be used for therapeutic intervention.
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The effect of ozone exposure on the ability of human surfactant protein a variants to stimulate cytokine production.
TL;DR: It is concluded that ozone exposure modulates the ability of SP-A variants to stimulate cytokines by THP-1 cells, and that SP-As from bronchoalveolar lavage fluid of certain alveolar proteinosis patients may be oxidized in vivo.
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Human SP-A protein variants derived from one or both genes stimulate TNF-α production in the THP-1 cell line
TL;DR: The data suggest that theSP-A-induced increases in TNF-alpha levels differ among SP-A variants and appear to be affected by SP- a genotype and whether SP- A is derived from one or both genes.