Gustavo Kourí

TL;DR: It is argued that a single mutation in the NS1 gene contributes to viral survival or replication efficiency, resulting in enhanced infection in the presence of enhancing antibodies, a phenomenon that is term increased virus "fitness" in contrast to "virulence," an intrinsic property of the virus.

TL;DR: The results showed total conservation of the E gene sequence for these isolates suggesting that the selection of envelope gene escape mutants was not the determinant of increased disease severity, suggesting that this “American/Asian” genotype has gradually dispersed across the Caribbean region during the past 5 years.

TL;DR: This report summarizes the consensus comments of the expert group after oral and written consultation and should stimulate a debate within the scientific community and serve as a recommendation for future actions by international or regional funding agencies in the area of NIDs in LAC.

TL;DR: It is suggested that some clinical manifestations that appear during convalescence after suffering the severe disease could last for several months.

TL;DR: Considering that a safe and accessible vaccine is now unavailable, basic principles of vector control combined with political willingness, inter-sectoral involvement, active community participation and the tightening of health legislation were examined as the only viable solution at present.