H
H.-G. Schnürch
Researcher at University of Düsseldorf
Publications - 23
Citations - 609
H.-G. Schnürch is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Breast cancer & Epidermal growth factor. The author has an hindex of 7, co-authored 22 publications receiving 581 citations.
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Journal ArticleDOI
Multistep carcinogenesis of breast cancer and tumour heterogeneity.
TL;DR: This review deals only with the factors that are involved in the conversion of a normal breast cell into a malignant cell rather than those required for invasion and metastases.
Journal ArticleDOI
Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer
M. W. Beckmann,Frauke Picard,H.X. An,C. R. C. van Roeyen,S. I. Dominik,D. S. Mosny,H.-G. Schnürch,H. G. Bender,Dieter Niederacher +8 more
TL;DR: Microsatellite analyses combined with detection of fluorescent-labelled PCR products by an automated laser DNA sequencer can be used for routine determination of LOH in sporadic breast cancer.
Journal ArticleDOI
Diagnosis, Therapy and Follow-up Care of Vulvar Cancer and its Precursors. Guideline of the DGGG and DKG (S2k-Level, AWMF Registry Number 015/059, November 2015.
H.-G. Schnürch,Sven Ackermann,C. D. Alt,Jana Barinoff,Carsten Böing,Christian Dannecker,Friederike Gieseking,Andreas R. Günthert,P Hantschmann,L.-C. Horn,R. Kürzl,Peter Mallmann,Simone Marnitz,Grit Mehlhorn,Carolin C. Hack,Martin C. Koch,U. Torsten,W. Weikel,Linn Wölber,Monika Hampl +19 more
TL;DR: This updated guideline aims to disseminate the most recent recommendations, which are much clearer and more individualized, and is intended to create a basis for the assessment and improvement of quality care in hospitals.
Journal ArticleDOI
ERBB2 gene amplification detected by fluorescent differential polymerase chain reaction in paraffin-embedded breast carcinoma tissues.
H.X. An,H.X. An,Dieter Niederacher,M. W. Beckmann,Uwe-Jochen Göhring,A. Scharl,Frauke Picard,Claudiavan van Roeyen,H.-G. Schnürch,Hans Georg Bender +9 more
TL;DR: In univariate analysis, ERBB2 gene amplification showed no significant correlation with clinical outcome, either in the whole population or in the subgroup defined by positive axillary lymph‐node metastases, however, within the node‐negative subgroup, patients with ERBB1 gene amplification had significantly decreased relapse‐free survival and overall survival.
Journal ArticleDOI
Expression Analyses of Epidermal Growth Factor Receptor and HER-2/neu: No Advantage of Prediction of Recurrence or Survival in Breast Cancer Patients
M. W. Beckmann,Dieter Niederacher,Gero Massenkeil,Boris Tutschek,Andreas Beckmann,Gerhard Schenko,H.-G. Schnürch,Hans Bender +7 more
TL;DR: Neither the evaluation of a single parameter of the erbB family nor the combination of both parameters showed a significant correlation with the disease-free and the overall survival of the individual patient with breast cancer and only the expression of the progesterone receptor correlated with a better overall survival.