H
H Marquardt
Publications - 2
Citations - 537
H Marquardt is an academic researcher. The author has contributed to research in topics: Chinese hamster ovary cell & Transforming growth factor beta. The author has an hindex of 2, co-authored 2 publications receiving 524 citations.
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Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide.
TL;DR: Highly purified recombinant TGF-beta 1 had the same specific biological activity as natural TGF -beta 1 and inhibited mink lung cell proliferation at 50 to 60 pM concentrations.
Journal ArticleDOI
Type 1 transforming growth factor beta: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells.
L E Gentry,Nancy R. Webb,G J Lim,Amy M. Brunner,J E Ranchalis,Daniel R. Twardzik,M N Lioubin,H Marquardt,Anthony F. Purchio +8 more
TL;DR: The availability of biologically active recombinant type 1 TGF-beta and precursor forms should provide a means to examine the structure, function, and potential in vivo therapeutic use of this growth factor.