H
H T Cuypers
Researcher at University of Amsterdam
Publications - 3
Citations - 776
H T Cuypers is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Infectivity & Phenotype. The author has an hindex of 3, co-authored 3 publications receiving 776 citations.
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Journal ArticleDOI
Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex.
M. Tersmette,R. E. Y. De Goede,B. J. M. Al,I.N. Winkel,Rob A. Gruters,H T Cuypers,H. G. Huisman,Frank Miedema +7 more
TL;DR: Evidence was obtained that the high replication rate of syncytium-inducing isolates observed during primary isolation may be due to higher infectivity of these isolates, and the finding that only syncyTium- inducing isolates could be transmitted to the H9 cell line is compatible with thisHigher infectivity.
Journal ArticleDOI
Phenotypic heterogeneity in a panel of infectious molecular human immunodeficiency virus type 1 clones derived from a single individual.
M. Groenink,Ron A. M. Fouchier,R. E. Y. De Goede,F. De Wolf,Rob A. Gruters,H T Cuypers,H. G. Huisman,M. Tersmette +7 more
TL;DR: With these clones, it is demonstrated that SI capacity and tropism for the H9 T-cell line, almost invariably coupled in primary HIV-1 isolates, are discernible properties and obtained evidence that T- cell line tropism is not caused by differences in level of HIV- 1 expression but most probably is restricted at the level of virus entry.
Journal ArticleDOI
Tumor progression in murine leukemia virus-induced T-cell lymphomas: monitoring clonal selections with viral and cellular probes.
TL;DR: Moloney MuLV acted as a highly efficient insertional mutagen, able to activate different (putative) oncogenes in one cell lineage to induce oligoclonal tumors and exhibited a homing preference upon transplantation in syngeneic hosts and were differently affected by the route of transplantation.