H
H. Y. Ton
Researcher at University of Cambridge
Publications - 7
Citations - 136
H. Y. Ton is an academic researcher from University of Cambridge. The author has contributed to research in topics: Amberlite & Albumin. The author has an hindex of 5, co-authored 7 publications receiving 136 citations.
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Journal ArticleDOI
Albumin-coated Amberlite XAD-7 resin for hemoperfusion in acute liver failure. Part I: adsorption studies.
TL;DR: It is shown that HSA can be tightly bound to Amberlite XAD-7 without the use of chemical coupling agents and the adsorption conforms to Langmuir's isotherm.
Journal ArticleDOI
Albumin-coated Amberlite XAD-7 resin for hemoperfusion in acute liver failure. Part II: in vivo evaluation.
Robin D. Hughes,H. Y. Ton,Peter G. Langley,Michael Davies,M. Anwar Hanid,Peter Mellon,David B. A. Silk,Roger Williams +7 more
TL;DR: Preliminary results suggest albumin-coated Amberlite XAD-7 resin to be blood compatible and capable of removing protein-bound and middle molecular weight substances from patients with acute liver failure.
Journal ArticleDOI
Adsorption of human serum albumin to amberlite XAD‐7 resin
TL;DR: In the present study the conditions leading to tight binding of human serum albumin to the Amberlite XAD-7 resin without the use of chemical coupling agents have been defined andoretical analysis of the data suggest adsorption of a monolayer of albumin which is supported by the absence of visual surface coating on scanning electron micrographs.
Journal Article
The use of prostacyclin, PGI2, in the prevention of platelet aggregation during charcoal haemoperfusion.
TL;DR: Prostacyclin would be expected to be of considerable clinical value in the prevention of adverse platelet reactions to charcoal haemoperfusion when carried out in patients with fulminant hepatic failure.
Journal Article
The use of an in vitro haemoperfusion circuit to evaluate the blood compatibility of albumin-coated Amberlite XAD-7 resin.
TL;DR: Coating of XAD-7 resin with HSA improves its blood compatibility with respect to platelet losses and it is intended to use this preparation in a clinical trial of resin haemoperfusion in fulminant hepatic failure.