H
Haley M. Amemiya
Researcher at University of Michigan
Publications - 13
Citations - 995
Haley M. Amemiya is an academic researcher from University of Michigan. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 3, co-authored 9 publications receiving 439 citations. Previous affiliations of Haley M. Amemiya include Broad Institute & University of Washington.
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The ENCODE Blacklist: Identification of Problematic Regions of the Genome.
TL;DR: The ENCODE blacklist is defined- a comprehensive set of regions in the human, mouse, worm, and fly genomes that have anomalous, unstructured, or high signal in next-generation sequencing experiments independent of cell line or experiment.
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rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants
TL;DR: The finding that r DNA is affected by lithium acetate exposure suggested that rDNA copy number variants may be influential passenger mutations in standard strain construction in S. cerevisiae.
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Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast
Joseph C. Sanchez,Elizabeth X. Kwan,Thomas J. Pohl,Haley M. Amemiya,M. K. Raghuraman,Bonita J. Brewer +5 more
TL;DR: It is found that yeast cells with the orc4Y232C allele have a prolonged S-phase, due to compromised replication initiation at the ribosomal DNA (rDNA) locus located on chromosome XII, which provides additional evidence linking two essential cellular pathways—DNA replication and ribosome biogenesis.
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Nucleoid-associated proteins shape chromatin structure and transcriptional regulation across the bacterial kingdom.
TL;DR: In this article, the regulatory roles played by NAPs in several well-studied bacteria and use the resulting state of knowledge to provide a working definition for NAP, based on their function, binding pattern, and expression levels.
Posted ContentDOI
Dynamic landscape of protein occupancy across the Escherichia coli chromosome
TL;DR: This study demonstrates that global observations of protein occupancy combined with statistical inference can rapidly and systematically reveal the transcriptional regulatory and structural features of a bacterial genome.