H
Halgund Beck
Researcher at University of Tübingen
Publications - 2
Citations - 281
Halgund Beck is an academic researcher from University of Tübingen. The author has contributed to research in topics: Lanosterol & Allicin. The author has an hindex of 2, co-authored 2 publications receiving 265 citations.
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Journal ArticleDOI
Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures.
Rolf Gebhardt,Halgund Beck +1 more
TL;DR: The fact that allicin was the most effective inhibitor argues against the possibility that its degradation products, namely diallyl disulfide or allyl mercapatan might mediate its effects, a possibility that might be true, however, in the case of the vinyl-dithiins.
Journal ArticleDOI
Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells
TL;DR: It is concluded that a major point of inhibition at the late steps occurs at the level of lanosterol 14 alpha-demethylase, which influences cholesterol biosynthesis at different steps of this metabolic pathway.